Seiji Okada Selected Research

Janus Kinase 3

1/2019	Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models.
1/2015	Evaluation of antitumor effects of folate-conjugated methyl-β-cyclodextrin in melanoma.
9/2009	Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice.

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Seiji Okada Research Topics

Disease

72	Neoplasms (Cancer) 08/2022 - 09/2002
28	Cholangiocarcinoma 02/2022 - 06/2010
26	Infections 05/2022 - 09/2009
25	Spinal Cord Injuries (Spinal Cord Injury) 01/2021 - 01/2004
20	Primary Effusion Lymphoma 10/2022 - 09/2009
12	Neoplasm Metastasis (Metastasis) 08/2022 - 04/2012
10	Inflammation (Inflammations) 12/2022 - 07/2002
10	Acquired Immunodeficiency Syndrome (AIDS) 10/2016 - 04/2005
9	Lymphoma (Lymphomas) 03/2020 - 09/2009
8	Carcinogenesis 10/2020 - 05/2007
7	Cicatrix (Scar) 01/2022 - 12/2005
6	Rheumatoid Arthritis 11/2022 - 12/2018
6	Wounds and Injuries (Trauma) 10/2022 - 04/2008
5	Gliosis 01/2021 - 06/2005
5	Melanoma (Melanoma, Malignant) 01/2018 - 08/2013
5	Ascites 06/2017 - 09/2009
4	Congenital Abnormalities (Deformity) 08/2022 - 10/2021
4	Pain (Aches) 01/2022 - 04/2012
4	Leukemia 03/2021 - 08/2007
4	Hematologic Neoplasms (Hematological Malignancy) 01/2016 - 03/2012
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2022 - 01/2013
3	Fibrosis (Cirrhosis) 01/2022 - 01/2017
3	Hypoxia (Hypoxemia) 06/2021 - 01/2016
3	Breast Neoplasms (Breast Cancer) 01/2021 - 09/2014
3	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020 - 01/2012
3	HIV Infections (HIV Infection) 09/2018 - 09/2016
3	Spinal Cord Diseases 01/2018 - 04/2012
3	Disease Progression 01/2018 - 04/2005
3	Lung Neoplasms (Lung Cancer) 01/2017 - 01/2014
2	Osteoporosis 11/2022 - 10/2021
2	Multiple Myeloma 10/2022 - 05/2022
2	Hematoma 05/2022 - 03/2013
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2021 - 01/2016
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 02/2015
2	Genomic Instability 10/2020 - 03/2004
2	Hyperpigmentation 03/2020 - 04/2014
2	Hyperglycemia 01/2020 - 10/2014
2	Sarcoma (Soft Tissue Sarcoma) 11/2019 - 01/2017
2	Spinal Cord Compression 11/2019 - 01/2018
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2019 - 11/2015

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2002
12	CytokinesIBA 01/2022 - 07/2002
8	Pharmaceutical PreparationsIBA 01/2022 - 04/2014
6	Therapeutic UsesIBA 01/2021 - 08/2007
6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 03/2004
6	Transcription Factors (Transcription Factor)IBA 01/2017 - 01/2011
5	Antineoplastic Agents (Antineoplastics)IBA 05/2019 - 08/2013
5	Liposomes (Liposome)IBA 12/2017 - 03/2010
5	NF-kappa B (NF-kB)IBA 01/2014 - 11/2007
4	Small Interfering RNA (siRNA)IBA 11/2020 - 07/2012
4	Interleukin-6 (Interleukin 6)IBA 02/2019 - 06/2005
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 07/2012
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2016 - 03/2013
4	cepharanthineIBA 05/2014 - 09/2009
4	src-Family KinasesIBA 03/2012 - 04/2005
3	Monoclonal AntibodiesIBA 10/2022 - 06/2021
3	AcidsIBA 07/2021 - 03/2020
3	Histones (Histone)IBA 01/2021 - 01/2017
3	Biological ProductsIBA 01/2021 - 12/2015
3	Messenger RNA (mRNA)IBA 10/2020 - 07/2012
3	Nuclear Proteins (Protein, Nuclear)IBA 10/2020 - 07/2012
3	Janus Kinase 3IBA 01/2019 - 09/2009
3	VimentinIBA 05/2018 - 01/2012
3	CollagenIBA 12/2017 - 11/2011
3	Proteasome Endopeptidase Complex (Proteasome)IBA 06/2017 - 09/2013
3	CyclodextrinsIBA 01/2015 - 10/2014
3	Folic Acid (Vitamin M)FDA LinkGeneric 01/2015 - 03/2014
2	C-Reactive ProteinIBA 11/2022 - 05/2022
2	Indicators and Reagents (Reagents)IBA 11/2022 - 08/2015
2	Glycoproteins (Glycoprotein)IBA 10/2022 - 05/2022
2	Carrier Proteins (Binding Protein)IBA 02/2022 - 01/2022
2	Imatinib Mesylate (Gleevec)FDA Link 01/2022 - 01/2013
2	Tyrosine Kinase InhibitorsIBA 01/2022 - 01/2018
2	acanthoic acidIBA 12/2021 - 01/2021
2	Interleukin-33IBA 10/2021 - 01/2020
2	Cyclin D1IBA 06/2021 - 01/2018
2	IntegrinsIBA 01/2021 - 07/2017
2	Fibronectins (Fibronectin)IBA 01/2021 - 10/2017
2	Conditioned Culture MediaIBA 01/2021 - 02/2019
2	LipidsIBA 01/2021 - 12/2014
2	Propidium (Propidium Iodide)IBA 01/2021 - 08/2015
2	AntioxidantsIBA 03/2020 - 01/2018
2	ChromatinIBA 11/2019 - 03/2012
2	Tumor Biomarkers (Tumor Markers)IBA 01/2019 - 01/2012
2	PhytochemicalsIBA 01/2019 - 01/2014
2	PeriostinIBA 08/2018 - 03/2017

Therapy/Procedure

28	Therapeutics 01/2022 - 04/2002
13	Transplantation 09/2021 - 01/2004
11	Drug Therapy (Chemotherapy) 01/2022 - 01/2010
5	Immunotherapy 10/2022 - 08/2015
4	Osteotomy 01/2022 - 09/2013
4	Decompression 11/2016 - 04/2012
3	Heavy Ion Radiotherapy 11/2019 - 01/2017
3	Highly Active Antiretroviral Therapy (HAART) 08/2019 - 03/2010
2	Metastasectomy 07/2022 - 01/2022
2	Operative Surgical Procedures 01/2022 - 10/2021
2	Laminectomy 01/2022 - 01/2012
2	Intraperitoneal Injections 05/2021 - 09/2009
2	Cell Transplantation 04/2021 - 01/2004
2	Hematopoietic Stem Cell Transplantation 01/2021 - 01/2016